> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > NOS1AP Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM06751G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NOS1AP antibody (Center).
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Molecular Weight |
56150 Da
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
437-466 aa
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Target |
This NOS1AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-466 amino acids from the Central region of human NOS1AP.
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Isotype |
Rabbit Ig
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Symbol |
CAPON, KIAA0464
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GeneID |
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UniProt ID |
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Function |
Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity).
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Summary |
This gene encodes a cytosolic protein that binds to thesignaling molecule, neuronal nitric oxide synthase (nNOS). Thisprotein has a C-terminal PDZ-binding domain that mediatesinteractions with nNOS and an N-terminal phosphotyrosine binding(PTB) domain that binds to the small monomeric G protein, Dexras1.Studies of the related mouse and rat proteins have shown that thisprotein functions as an adapter protein linking nNOS to specifictargets, such as Dexras1 and the synapsins. Alternative splicingresults in multiple transcript variants encoding differentisoforms.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, E
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Dilution |
WB~~1:1000
FC~~1:10~50
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Synonyms |
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein, C-terminal PDZ ligand of neuronal nitric oxide synthase protein, Nitric oxide synthase 1 adaptor protein, NOS1AP, CAPON, KIAA0464
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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