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FLNB Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APR16004G 0.1 mg / $495

FLNB Antibody (internal region)

Brand

Leading Biology

Catalog Number

APR16004G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FLNB antibody (internal region).

Molecular Weight

278164 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line Note=In differentiating myotubes, isoform 1, isoform 2 and isoform 3 are localized diffusely throughout the cytoplasm with regions of enrichment at the longitudinal actin stress fiber. In differentiated tubes, isoform 1 is also detected within the Z- lines Isoform 3: Cytoplasm, cytoskeleton. Note=Predominantly localized at actin stress fibers

Host

Goat

Isotype

IgG

Symbol

FLN1L, FLN3, TABP, TAP

GeneID

UniProt ID

Function

Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoform 6 accelerates muscle differentiation in vitro.

Summary

This antibody is expected to recognise all reported isoforms (NP_001448.2; NP_001157789.1; NP_001157790.1; NP_001157791.1).

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

E

Synonyms

Filamin-B, FLN-B, ABP-278, ABP-280 homolog, Actin-binding-like protein, Beta-filamin, Filamin homolog 1, Fh1, Filamin-3, Thyroid autoantigen, Truncated actin-binding protein, Truncated ABP, FLNB, FLN1L, FLN3, TABP, TAP

Images

Specification

Quantity

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