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PEX12 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM08662G 100 μl / $545

PEX12 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM08662G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PEX12 antibody (Center).

Molecular Weight

40797 Da

Cellular Localization

Antigen Cellular Localization: Peroxisome membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

131-158 aa

Target

This PEX12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-158 amino acids from the Central region of human PEX12.

Isotype

Rabbit Ig

Symbol

PAF3

GeneID

UniProt ID

Function

Required for protein import into peroxisomes.

Summary

Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Peroxisome assembly protein 12, Peroxin-12, Peroxisome assembly factor 3, PAF-3, PEX12, PAF3

Images

Western blot analysis of PEX12 Antibody (Center) (Cat. AMM08662G) in mouse spleen tissue lysates (35ug/lane). PEX12 (arrow) was detected using the purified Pab.

Specification

Quantity

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