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CD24 Antibody (N-Term)

APG02485G Product Datasheet Protocol

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APG02485G		100 μl / $545

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Leading Biology Inc.

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CD24 Antibody (N-Term)

Brand	Leading Biology	Catalog Number	APG02485G
Product Type	Polyclonal Antibodies	Field of Research
Product Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD24 antibody (N-Term).
Molecular Weight	8097 Da
Cellular Localization	Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor.
Host	Rabbit
Species Reactivity	Human
Immunogen	1-30 aa
Target	This CD24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CD24.
Isotype	Rabbit Ig
Symbol	CD24A
GeneID	100133941
UniProt ID	P25063
Function	Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
Summary	CD24 is a sialoglycoprotein that is expressed on mature granulocytes and in many B cells. This protein is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface.
Form	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage & Stability	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Applications	WB, IHC-P, FC, E
Dilution	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
Synonyms	Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, CD24, CD24, CD24A
Images	CD24 Antibody (N-Term) (Cat. APG02485G) western blot analysis in Raji,Ramos cell line and rat cerebellum tissue lysates (35ug/lane).This demonstrates the CD24 antibody detected the CD24 protein (arrow). Western blot analysis of CD24 Antibody (N-Term) (Cat. APG02485G) in MCF-7 cell line lysates (35ug/lane). CD24 (arrow) was detected using the purified Pab. Formalin-fixed and paraffin-embedded human breast carcinoma reacted with CD24 Antibody (N-Term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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