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GHRHR Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR14110G 100 μl / $545

GHRHR Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR14110G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GHRHR antibody (C-term).

Molecular Weight

47402 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Immunogen

367-397 aa

Target

This GHRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-397 amino acids from the C-terminal region of human GHRHR.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.

Summary

GHRHR is a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in GHRHR gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Growth hormone-releasing hormone receptor, GHRH receptor, Growth hormone-releasing factor receptor, GRF receptor, GRFR, GHRHR

Images

Western blot analysis of GHRHR antibody (C-term) (Cat. APR14110G) in K562 cell line lysates (35ug/lane). GHRHR (arrow) was detected using the purified Pab.

Specification

Quantity

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