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PAT1(APPBP2) Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR14237G 100 μl / $545

PAT1(APPBP2) Antibody (Center)

Brand

Leading Biology

Catalog Number

APR14237G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAT1(APPBP2) antibody (Center).

Molecular Weight

66853 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein Note=Associated with membranes and microtubules

Host

Rabbit

Species Reactivity

Human

Immunogen

242-271 aa

Target

This PAT1(APPBP2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-271 amino acids from the Central region of human PAT1(APPBP2).

Isotype

Rabbit Ig

Symbol

KIAA0228, PAT1

GeneID

UniProt ID

Function

May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

Summary

APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This protein has been found to be highly expressed in breast cancer.

Form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, APP-BP2, Protein interacting with APP tail 1, APPBP2, KIAA0228, PAT1

Images

Western blot analysis of anti-PAT1(APPBP2) Antibody (Center) (Cat. APR14237G) in HL60 cell line lysates (35ug/lane). PAT1(arrow) was detected using the purified Pab.

Specification

Quantity

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