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IL1A-S87 Antibody

Catalog # Availability Size / Price Inquiry
APR10888G 100 μl / $545

IL1A-S87 Antibody

Brand

Leading Biology

Catalog Number

APR10888G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL1A-S87 antibody.

Molecular Weight

30607 Da

Cellular Localization

Antigen Cellular Localization: Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins

Host

Rabbit

Species Reactivity

Human

Immunogen

65-94 aa

Target

This IL1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from human IL1A.

Isotype

Rabbit Ig

Symbol

IL1F1

GeneID

UniProt ID

Function

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Summary

IL1A is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1, IL1A, IL1F1

Images

Western blot analysis of IL1A (arrow) using rabbit polyclonal IL1A-pS87 (Cat. APR10888G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the IL1A gene (Lane 2) (Origene Technologies).

Specification

Quantity

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