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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Claudin 2 (CLDN2) Antibody (N-term)

Claudin 2 (CLDN2) Antibody (N-term)

Catalog # Availability Size / Price Inquiry
AMM08605G 100 μl / $545

Claudin 2 (CLDN2) Antibody (N-term)

Brand

Leading Biology

Catalog Number

AMM08605G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Claudin 2 (CLDN2) antibody (N-term).

Molecular Weight

24549 Da

Cellular Localization

Antigen Cellular Localization: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

135-164 aa

Target

This Claudin 2 (CLDN2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the N-terminal region of human Claudin 2 (CLDN2).

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.

Summary

Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Claudin-2, SP82, CLDN2

Images

Western blot analysis of anti-CLDN2 Antibody (N-term) (Cat. AMM08605G) in mouse heart tissue lysates (35ug/lane). CLDN2(arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CLDN2 (Human N-term) (Cat. AMM08605G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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