> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Claudin 2 (CLDN2) Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMM08605G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Claudin 2 (CLDN2) antibody (N-term).
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Molecular Weight |
24549 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
135-164 aa
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Target |
This Claudin 2 (CLDN2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the N-terminal region of human Claudin 2 (CLDN2).
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.
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Summary |
Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Claudin-2, SP82, CLDN2
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Images |
Western blot analysis of anti-CLDN2 Antibody (N-term) (Cat. AMM08605G) in mouse heart tissue lysates (35ug/lane). CLDN2(arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CLDN2 (Human N-term) (Cat. AMM08605G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Leading Biology Inc.
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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