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ATP4B Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR10860G 100 μl / $545

ATP4B Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR10860G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATP4B antibody (N-term).

Molecular Weight

33367 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

52-78 aa

Target

This ATP4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human ATP4B.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity.

Summary

ATP4B belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Synonyms

Potassium-transporting ATPase subunit beta, Gastric H(+)/K(+) ATPase subunit beta, Proton pump beta chain, ATP4B

Images

Western blot analysis of ATP4B Antibody (N-term) (Cat. APR10860G) in mouse heart tissue lysates (35ug/lane).ATP4B (arrow) was detected using the purified Pab.

ATP4B Antibody (N-term) (Cat. APR10860G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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