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RDH10 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR10919G 100 μl / $545

RDH10 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR10919G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RDH10 antibody (Center).

Molecular Weight

38087 Da

Cellular Localization

Antigen Cellular Localization: Microsome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

106-135 aa

Target

This RDH10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the Central region of human RDH10.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.

Summary

RDH10 generates all-trans retinal from all-trans retinol and may plan an important role in the photic visual cycle. All-trans retinal is isomerized to 11-cis retinal by the retinal G protein-coupled receptor (RGR; MIM 600342) when the retinal pigment epithelium (RPE) is illuminated.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Synonyms

Retinol dehydrogenase 10, RDH10

Images

RDH10 Antibody (Center) (Cat. APR10919G) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the RDH10 antibody detected the RDH10 protein (arrow).

RDH10 Antibody (Center) (Cat. APR10919G) immunohistochemistry analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RDH10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

RDH10 Antibody (Center) (Cat. APR10919G) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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