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TAS2R43 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR14263G 100 μl / $545

TAS2R43 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR14263G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TAS2R43 antibody (Center).

Molecular Weight

35599 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia

Host

Rabbit

Species Reactivity

Human

Immunogen

135-163 aa

Target

This TAS2R43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-163 amino acids from the Central region of human TAS2R43.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).

Summary

Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May acts as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Taste receptor type 2 member 43, T2R43, Taste receptor type 2 member 52, T2R52, TAS2R43

Images

TAS2R43 Antibody (Center) (Cat. APR14263G) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TAS2R43 antibody detected the TAS2R43 protein (arrow).

Specification

Quantity

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