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ATP6V1C2 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR10861G 100 μl / $545

ATP6V1C2 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR10861G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATP6V1C2 antibody (Center).

Molecular Weight

48759 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

276-304 aa

Target

This ATP6V1C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the Central region of human ATP6V1C2.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Summary

This gene encodes a component of vacuolar ATPase(V-ATPase), a multisubunit enzyme that mediates acidification ofeukaryotic intracellular organelles. V-ATPase dependent organelleacidification is necessary for such intracellular processes asprotein sorting, zymogen activation, receptor-mediated endocytosis,and synaptic vesicle proton gradient generation. V-ATPase iscomposed of a cytosolic V1 domain and a transmembrane V0 domain.The V1 domain consists of three A,three B, and two G subunits, aswell as a C, D, E, F, and H subunit. The V1 domain contains the ATPcatalytic site. This gene encodes alternate transcriptional splicevariants, encoding different V1 domain C subunit isoforms.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

V-type proton ATPase subunit C 2, V-ATPase subunit C 2, Vacuolar proton pump subunit C 2, ATP6V1C2

Images

ATP6V1C2 Antibody (Center) (Cat. APR10861G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ATP6V1C2 antibody detected the ATP6V1C2 protein (arrow).

Specification

Quantity

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