> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ATP6V1C2 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR10861G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ATP6V1C2 antibody (Center).
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Molecular Weight |
48759 Da
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
276-304 aa
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Target |
This ATP6V1C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the Central region of human ATP6V1C2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
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Summary |
This gene encodes a component of vacuolar ATPase(V-ATPase), a multisubunit enzyme that mediates acidification ofeukaryotic intracellular organelles. V-ATPase dependent organelleacidification is necessary for such intracellular processes asprotein sorting, zymogen activation, receptor-mediated endocytosis,and synaptic vesicle proton gradient generation. V-ATPase iscomposed of a cytosolic V1 domain and a transmembrane V0 domain.The V1 domain consists of three A,three B, and two G subunits, aswell as a C, D, E, F, and H subunit. The V1 domain contains the ATPcatalytic site. This gene encodes alternate transcriptional splicevariants, encoding different V1 domain C subunit isoforms.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
V-type proton ATPase subunit C 2, V-ATPase subunit C 2, Vacuolar proton pump subunit C 2, ATP6V1C2
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Images |
ATP6V1C2 Antibody (Center) (Cat. APR10861G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ATP6V1C2 antibody detected the ATP6V1C2 protein (arrow). |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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