> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > UPK3B Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM08702G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UPK3B antibody (Center).
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Molecular Weight |
33882 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
192-219 aa
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Target |
This UPK3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human UPK3B.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).
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Summary |
UPK3B is a minor component of the apical plaques ofmammalian urothelium that binds and dimerizes with uroplakin-1b(UPK1B; MIM 602380), one of the major conserved urothelium membraneproteins. The other major conserved integral membrane proteins ofurothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), andUPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).[suppliedby OMIM].
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Uroplakin-3b, UP3b, Uroplakin IIIb, UPIIIb, p35, UPK3B
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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