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ATL1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR14093G 100 μl / $545

ATL1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR14093G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATL1 antibody (C-term).

Molecular Weight

63544 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, axon

Host

Rabbit

Species Reactivity

Human

Immunogen

477-504 aa

Target

This ATL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-504 amino acids from the C-terminal region of human ATL1.

Isotype

Rabbit Ig

Symbol

GBP3, SPG3A

GeneID

UniProt ID

Function

GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development.

Summary

The protein encoded by this gene is a GTPase and a Golgibody transmembrane protein. The encoded protein can form ahomotetramer and has been shown to interact with spastin and withmitogen-activated protein kinase kinase kinase kinase 4. Thisprotein may be involved in axonal maintenance as evidenced by thefact that defects in this gene are a cause of spastic paraplegiatype 3. Three transcript variants encoding two different isoformshave been found for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Atlastin-1, 365-, Brain-specific GTP-binding protein, GTP-binding protein 3, GBP-3, hGBP3, Guanine nucleotide-binding protein 3, Spastic paraplegia 3 protein A, ATL1, GBP3, SPG3A

Images

ATL1 Antibody (C-term) (Cat. APR14093G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ATL1 antibody detected the ATL1 protein (arrow).

Specification

Quantity

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