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STAR Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR10929G 100 μl / $545

STAR Antibody (Center)

Brand

Leading Biology

Catalog Number

APR10929G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STAR antibody (Center).

Molecular Weight

31914 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion.

Host

Rabbit

Species Reactivity

Human

Immunogen

88-117 aa

Target

This STAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human STAR.

Isotype

Rabbit Ig

Symbol

STARD1

GeneID

UniProt ID

Function

Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

Summary

The protein encoded by this gene plays a key role in theacute regulation of steroid hormone synthesis by enhancing theconversion of cholesterol into pregnenolone. This protein permitsthe cleavage of cholesterol into pregnenolone by mediating thetransport of cholesterol from the outer mitochondrial membrane tothe inner mitochondrial membrane. Mutations in this gene are acause of congenital lipoid adrenal hyperplasia (CLAH), also calledlipoid CAH. A pseudogene of this gene is located on chromosome 13.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Steroidogenic acute regulatory protein, mitochondrial, StAR, START domain-containing protein 1, StARD1, STAR, STARD1

Images

STAR Antibody (Center) (Cat. APR10929G) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the STAR antibody detected the STAR protein (arrow).

Specification

Quantity

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