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CYTH4 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMM08611G 100 μl / $545

CYTH4 Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMM08611G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYTH4 antibody (C-term).

Molecular Weight

45672 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Peripheral membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

291-319 aa

Target

This CYTH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human CYTH4.

Isotype

Rabbit Ig

Symbol

CYT4, PSCD4

GeneID

UniProt ID

Function

Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.

Summary

The protein encoded by this gene is a member of the PSCDfamily. Members of this family have identical structuralorganization that consists of an N-terminal coiled-coil motif, acentral Sec7 domain, and a C-terminal pleckstrin homology (PH)domain. The coiled-coil motif is involved in homodimerization, theSec7 domain contains guanine-nucleotide exchange protein (GEP)activity, and the PH domain interacts with phospholipids and isresponsible for association of PSCDs with membranes. Members ofthis family appear to mediate the regulation of protein sorting andmembrane trafficking. The encoded protein exhibits GEP activity invitro with both ARF1 and ARF5 but is inactive with ARF6. Thestructures of this gene and CYTH1 are very similar. [provided byRefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Cytohesin-4, PH, SEC7 and coiled-coil domain-containing protein 4, CYTH4, CYT4, PSCD4

Images

CYTH4 Antibody (C-term) (Cat. AMM08611G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the CYTH4 antibody detected the CYTH4 protein (arrow).

Specification

Quantity

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