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DNAH2 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
AMM08617G 100 μl / $545

DNAH2 Antibody (N-term)

Brand

Leading Biology

Catalog Number

AMM08617G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DNAH2 antibody (N-term).

Molecular Weight

507698 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton, cilium axoneme

Host

Rabbit

Species Reactivity

Human

Immunogen

440-468 aa

Target

This DNAH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-468 amino acids from the N-terminal region of human DNAH2.

Isotype

Rabbit Ig

Symbol

DNAHC2, DNHD3, KIAA1503

GeneID

UniProt ID

Function

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity).

Summary

Dyneins are microtubule-associated motor protein complexescomposed of several heavy, light, and intermediate chains. Theaxonemal dyneins, found in cilia and flagella, are components ofthe outer and inner dynein arms attached to the peripheralmicrotubule doublets. DNAH2 is an axonemal inner arm dynein heavychain (Chapelin et al., 1997 [PubMed 9256245]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Dynein heavy chain 2, axonemal, Axonemal beta dynein heavy chain 2, Ciliary dynein heavy chain 2, Dynein heavy chain domain-containing protein 3, DNAH2, DNAHC2, DNHD3, KIAA1503

Images

DNAH2 Antibody (N-term) (Cat. AMM08617G) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the DNAH2 antibody detected the DNAH2 protein (arrow).

Specification

Quantity

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