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PSCA Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM08670G 100 μl / $545

PSCA Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM08670G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PSCA antibody (Center).

Molecular Weight

12912 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor.

Host

Rabbit

Species Reactivity

Human

Immunogen

56-85 aa

Target

This PSCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the Central region of human PSCA.

Isotype

Rabbit Ig

UniProt ID

Function

May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.

Summary

PSCA is a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. It is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Prostate stem cell antigen, PSCA

Images

PSCA Antibody (Center) (Cat. AMM08670G) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the PSCA antibody detected the PSCA protein (arrow).

PSCA Antibody (Center) (Cat. AMM08670G)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PSCA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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