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TM55B Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APC00042G 100 μl / $545

TM55B Antibody (C-term)

Brand

Leading Biology

Catalog Number

APC00042G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TM55B antibody (C-term).

Molecular Weight

29470 Da

Cellular Localization

Antigen Cellular Localization: Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

183-211 aa

Target

This TM55B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-211 amino acids from the C-terminal region of human TM55B.

Isotype

Rabbit Ig

Symbol

C14orf9

GeneID

UniProt ID

Function

Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4- bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3- monophosphate.

Summary

TMEM55B catalyzes the degradation of phosphatidylinositol4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate(Ungewickell et al., 2005 [PubMed 16365287]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Synonyms

Type 1 phosphatidylinositol 4, 5-bisphosphate 4-phosphatase, Type 1 PtdIns-4, 5-P2 4-Ptase, PtdIns-4, 5-P2 4-Ptase I, Transmembrane protein 55B, TMEM55B, C14orf9

Images

TM55B Antibody (C-term) (Cat. APC00042G) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the TM55B antibody detected the TM55B protein (arrow).

TM55B Antibody (C-term) (Cat. APC00042G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TM55B Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

TM55B Antibody (C-term) (Cat. APC00042G) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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