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UGT2B15 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM05348G 100 μl / $545

UGT2B15 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM05348G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UGT2B15 antibody (Center).

Molecular Weight

61036 Da

Cellular Localization

Antigen Cellular Localization: Microsome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

156-185 aa

Target

This UGT2B15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human UGT2B15.

Isotype

Rabbit Ig

Symbol

UGT2B8

GeneID

UniProt ID

Function

UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.

Summary

The UGTs are of major importance in the conjugation andsubsequent elimination of potentially toxic xenobiotics andendogenous compounds. UGT2B8 demonstrates reactivity with estriol.See UGT2B4 (MIM 600067).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 IF~~1:10~50 FC~~1:10~50

Synonyms

UDP-glucuronosyltransferase 2B15, UDPGT 2B15, HLUG4, UDP-glucuronosyltransferase 2B8, UDPGT 2B8, UDPGTh-3, UGT2B15, UGT2B8

Images

UGT2B15 Antibody (Center) (Cat. AMM05348G) western blot analysis in NCI-H460(lane 1),HepG2(lane 2),ZR-75-1(lane 3) cell line lysates (35ug/lane).This demonstrates the UGT2B15 antibody detected the UGT2B15 protein (arrow).

UGT2B15 Antibody (Center) (Cat. AMM05348G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of UGT2B15 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Confocal immunofluorescent analysis of UGT2B15 Antibody (Center) ( AMM05348G) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Specification

Quantity

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