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OTX2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR14235G 100 μl / $545

OTX2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR14235G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OTX2 antibody (C-term).

Molecular Weight

31636 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human

Immunogen

261-289 aa

Target

This OTX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human OTX2.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.

Summary

This gene encodes a member of the bicoid sub-family ofhomeodomain-containing transcription factors. The encoded proteinacts as a transcription factor and may play a role in brain andsensory organ development. A similar protein in mice is requiredfor proper forebrain development. Two transcript variants encodingdistinct isoforms have been identified for this gene. Otheralternative splice variants may exist, but their full lengthsequences have not been determined.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

Homeobox protein OTX2, Orthodenticle homolog 2, OTX2

Images

OTX2 Antibody (C-term) (Cat. APR14235G) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the OTX2 antibody detected the OTX2 protein (arrow).

OTX2 Antibody (C-term) (Cat. APR14235G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTX2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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