> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > BTG2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR14069G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BTG2 antibody (N-term).
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Molecular Weight |
17416 Da
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
33-61 aa
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Target |
This BTG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human BTG2.
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Isotype |
Rabbit Ig
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Symbol |
PC3
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GeneID |
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UniProt ID |
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Function |
Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.
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Summary |
The protein encoded by this gene is a member of theBTG/Tob family. This family has structurally related proteins thatappear to have antiproliferative properties. This encoded proteinis involved in the regulation of the G1/S transition of the cellcycle.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
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Synonyms |
Protein BTG2, BTG family member 2, NGF-inducible anti-proliferative protein PC3, BTG2, PC3
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Images |
BTG2 Antibody (N-term) (Cat. APR14069G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the BTG2 antibody detected the BTG2 protein (arrow).
BTG2 Antibody (N-term) (Cat. APR14069G)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BTG2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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