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BTG2 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR14069G 100 μl / $545

BTG2 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR14069G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BTG2 antibody (N-term).

Molecular Weight

17416 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

33-61 aa

Target

This BTG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human BTG2.

Isotype

Rabbit Ig

Symbol

PC3

GeneID

UniProt ID

Function

Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.

Summary

The protein encoded by this gene is a member of theBTG/Tob family. This family has structurally related proteins thatappear to have antiproliferative properties. This encoded proteinis involved in the regulation of the G1/S transition of the cellcycle.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

Protein BTG2, BTG family member 2, NGF-inducible anti-proliferative protein PC3, BTG2, PC3

Images

BTG2 Antibody (N-term) (Cat. APR14069G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the BTG2 antibody detected the BTG2 protein (arrow).

BTG2 Antibody (N-term) (Cat. APR14069G)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BTG2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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