> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > LANCL2 AntibodyBrand |
Leading Biology | Catalog Number |
APR06925G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LANCL2 Antibody.
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Molecular Weight |
Predicted: 50 kDa; Observed: 48 kDa
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Cell membrane. Note=Localizes to the juxta-nuclear vesicles. Associates with the cortical actin cytoskeleton. Cholesterol depletion by methyl-beta- cyclodextrin causes partial dissociation from the cell membrane in vitro and an enhanced cell detachment from the matrix in vivo Membrane-association is important for the increased cellular sensitivity to an anticancer drug (adriamycin)
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
LANCL2; LANCL2 antibody is human, mouse and rat reactive.
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Isotype |
IgG
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Symbol |
GPR69B, TASP
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GeneID |
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UniProt ID |
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Function |
Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes.
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Summary |
LANCL2 (LanC-like protein 2), also known as TASP (testis-specific adriamycin sensitivity protein) or GPR69B, is a 450 amino acid member of the LanC-like protein family (1). It is expressed highly in brain and testis and localized to the nucleus, cytoplasm and cell membrane (2,3). LANCL2 is necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes (3,4).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, E
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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