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RNF121 Antibody

Catalog # Availability Size / Price Inquiry
APR06922G 0.1 mg / $695

RNF121 Antibody

Brand

Leading Biology

Catalog Number

APR06922G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RNF121 Antibody.

Molecular Weight

Predicted: 24, 27, 36 kDa Observed: 28 kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

RNF121; RNF121 antibody is human, mouse and rat reactive. Multiple isoforms of RNF121 are known to exist.

Isotype

IgG

GeneID

UniProt ID

Summary

RNF121 is an evolutionarily conserved E3 ligase ring finger protein that is expressed in the endoplasmic reticulum (1). It acts downstream of the unfolded protein response regulator protein kinase-like endoplasmic reticulum kinase (PERK). Overexpression of RNF121 during the early stages of gonad development led to aberrations in germline development and gonad migration, suggesting that it plays a role in endoplasmic reticulum-associated degradation machinery (1).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, ICC, E

Images

Western blot analysis of RNF121 in MCF7 cell lysate with RNF121 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.

Immunocytochemistry of RNF121 in MCF7 cells with RNF121 antibody at 10 μg/ml.

Specification

Quantity

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