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SPINSTER Antibody

Catalog # Availability Size / Price Inquiry
APR06869G 0.1 mg / $695

SPINSTER Antibody

Brand

Leading Biology

Catalog Number

APR06869G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPINSTER Antibody.

Molecular Weight

Predicted: 58 kDa Observed: 70 kDa

Cellular Localization

Antigen Cellular Localization: Mitochondrion inner membrane; Multi-pass membrane protein. Note=Colocalizes with SDHB

Host

Rabbit

Species Reactivity

Human

Target

SPNS1; SPINSTER antibody is human specific. At least four isoforms of SPINSTER are known to exist. This antibody is predicted to not cross-react with other members of the spinster family of proteins.

Isotype

IgG

Symbol

SPIN1

GeneID

UniProt ID

Function

Sphingolipid transporter (By similarity). May be involved in necrotic or autophagic cell death.

Summary

SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily (1). SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death (2). The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function (1,3).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

Western blot analysis of SPINSTER in human placenta tissue lysate with SPINSTER antibody at (A) 1 and (B) 2 μg/ml.

Specification

Quantity

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