> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > BTLA AntibodyBrand |
Leading Biology | Catalog Number |
APR06838G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BTLA Antibody .
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Molecular Weight |
Predicted: 32 kDa Observed: 40kDa
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
BTLA; BTLA antibody is human specific. At least two isoforms of BTLA are known to exist.
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Function |
Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.
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Summary |
The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Images |
Western blot analysis of BTLA in Jurkat cell lysate at (A) 1 and (B) 2 μg/ml.
Immunohistochemistry of BTLA in human small intestine tissue with BTLA antibody at 2.5 μg/mL.
Immunofluorescence of BTLA in human small intestine tissue with BTLA antibody at 20 μg/mL. |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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