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BTLA Antibody

Catalog # Availability Size / Price Inquiry
APR06838G 0.1 mg / $695

BTLA Antibody

Brand

Leading Biology

Catalog Number

APR06838G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BTLA Antibody .

Molecular Weight

Predicted: 32 kDa Observed: 40kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human

Target

BTLA; BTLA antibody is human specific. At least two isoforms of BTLA are known to exist.

Isotype

IgG

GeneID

UniProt ID

Function

Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.

Summary

The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of BTLA in Jurkat cell lysate at (A) 1 and (B) 2 μg/ml.

Immunohistochemistry of BTLA in human small intestine tissue with BTLA antibody at 2.5 μg/mL.

Immunofluorescence of BTLA in human small intestine tissue with BTLA antibody at 20 μg/mL.

Specification

Quantity

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