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CEACAM5 Antibody

Catalog # Availability Size / Price Inquiry
APR06834G 0.1 mg / $695

CEACAM5 Antibody

Brand

Leading Biology

Catalog Number

APR06834G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CEACAM5 Antibody .

Molecular Weight

Predicted: 77 kDa Observed: 80kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

CEACAM5; CEACAM5 antibody is human, mouse and rat reactive. CEACAM5 antibody is predicted to not cross-react with other CEACAM protein family members.

Isotype

IgG

Symbol

CEA

GeneID

UniProt ID

Function

Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.

Summary

CEACAM5 is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily (1,2). CEACAM proteins are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (2). CEACAM5 has been shown to be overexpressed in a majority of carcinomas and has been suggested to be a intercellular adhesion molecule involved in cancer invasion and metastasis (3).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

Western blot analysis of CEACAM5 in rat lung tissue lysate with CEACAM5 antibody at (A) 1 and (B) 2 μg/ml.

Immunofluorescence of CEACAM5 in human lung tissue with CEACAM5 antibody at 20 μg/mL.

Specification

Quantity

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