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MLIP Antibody

Catalog # Availability Size / Price Inquiry
APR06742G 0.1 mg / $695

MLIP Antibody

Brand

Leading Biology

Catalog Number

APR06742G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MLIP Antibody.

Molecular Weight

50429 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Nucleus envelope. Nucleus, PML body

Host

Rabbit

Species Reactivity

Human

Target

MLIP; At least three isoforms of MLIP are known to exist.

Isotype

IgG

Symbol

C6orf142

GeneID

UniProt ID

Summary

MLIP Antibody: The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodies

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of MLIP in 293 cell lysate with MLIP antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry of MLIP in human heart tissue with MLIP antibody at 5 μg/mL.

Immunofluorescence of MLIP in human heart tissue with MLIP antibody at 20 μg/mL.

Specification

Quantity

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