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SPINK2 Antibody

Catalog # Availability Size / Price Inquiry
APR06739G 0.1 mg / $695

SPINK2 Antibody

Brand

Leading Biology

Catalog Number

APR06739G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPINK2 Antibody.

Molecular Weight

9291 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse

Target

SPINK2; SPINK2 antibody is predicted to not cross-react with other SPINK family members.

Isotype

IgG

GeneID

UniProt ID

Function

Strong inhibitor of acrosin in male and/or female genital tract. Also inhibits trypsin.

Summary

SPINK2 Antibody: Human serine proteinase inhibitor Kazal-type 2 (SPINK2) is required for maintaining normal spermatogenesis and potentially regulates serine protease-mediated apoptosis in male germ cells. It contains a typical kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. SPINK2 plays a role in the pathogenesis of hereditary and chronic pancreatitis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of SPINK2 in mouse heart tissue lysate with SPINK2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry of SPINK2 in mouse testis tissue with SPINK2 antibody at 2.5 μg/mL.

Immunofluorescence of SPINK2 in mouse testis tissue with SPINK2 antibody at 20 μg/mL.

Specification

Quantity

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