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RASSF6 Antibody

Catalog # Availability Size / Price Inquiry
APR06727G 0.1 mg / $695

RASSF6 Antibody

Brand

Leading Biology

Catalog Number

APR06727G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RASSF6 Antibody.

Molecular Weight

43384 Da

Host

Rabbit

Species Reactivity

Human

Target

RASSF6; At least four isoforms of RASSF6 are known to exist. RASSF6 antibody is predicted to not cross-react with other RASSF family members.

Isotype

IgG

GeneID

UniProt ID

Function

Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B (By similarity).

Summary

RASSF6 Antibody: RASSF family proteins are tumor suppressors that are frequently downregulated during the development of human cancer. RASSF6 (Ras association (RalGDS/AF-6) domain family member 6), a member of RASSF family, acts as a Ras effector protein / tumor suppressor. RASSF6 contains one Ras-associating domain and one SARAH domain. It is involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. Defects in RASSF6 may facilitate viral NFκ-B pathway and may play a vital role in infection.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

Western blot analysis of RASSF6 in 293 cell lysate with RASSF6 antibody at 1 μg/mL.

Specification

Quantity

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