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ATAD3A Antibody

Catalog # Availability Size / Price Inquiry
APR06709G 0.1 mg / $695

ATAD3A Antibody

Brand

Leading Biology

Catalog Number

APR06709G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATAD3A Antibody.

Molecular Weight

71369 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion matrix, mitochondrion nucleoid Note=In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane. The N- terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

ATAD3A; ATAD3A antibody is predicted to not cross-react with other ATAD protein family members. At least two isoforms are known to exist.

Isotype

IgG

GeneID

UniProt ID

Function

Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone- dependent steroidogenesis.

Summary

ATAD3A Antibody: ATAD3A is a member of the AAA ATPase family, a family of proteins that catalyze ATP into ADP and are involved in several cellular functions such as cell-cycle regulation, protein proteolysis and transport. The AAA ATPase family is characterized by a highly conserved AAA motif containing Walker homology sequences and imparting ATPase activity. Mitochondrial membrane proteins ATAD3A/B contribute to the stabilization of nucleoids and may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The gene encoding ATAD3A/B/C maps to human chromosome 1 and has been suggested to be an anti-apoptotic marker.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, ICC, E

Images

Western blot analysis of ATAD3A in Daudi cell lysate with ATAD3A antibody at 1 μg/mL .

Immunocytochemistry of ATAD3A in Daudi cells with ATAD3A antibody at 20 μg/mL.

Immunofluorescence of ATAD3A in Daudi cells with ATAD3A antibody at 20 μg/mL.

Specification

Quantity

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