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PLAC1 Antibody

Catalog # Availability Size / Price Inquiry
APR06679G  In Stock 0.1 mg / $695

PLAC1 Antibody

Brand

Leading Biology

Catalog Number

APR06679G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLAC1 Antibody.

Molecular Weight

23616 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Target

PLAC1;

Isotype

IgG

GeneID

UniProt ID

Function

May play a role in placental development.

Summary

PLAC1 Antibody: PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, ICC, E

Images

Western blot analysis of PLAC1 in human placenta tissue lysate with PLAC1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunocytochemistry of PLAC1 in HeLa cells with PLAC1 antibody at 10 μg/mL.

Immunofluorescence of PLAC1 in Hela cells with PLAC1 antibody at 20 μg/mL.

Specification

Quantity

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