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AFP Antibody

Catalog # Availability Size / Price Inquiry
APR06656G 0.1 mg / $695

AFP Antibody

Brand

Leading Biology

Catalog Number

APR06656G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AFP Antibody.

Molecular Weight

68678 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

AFP;

Isotype

IgG

Symbol

HPAFP

GeneID

UniProt ID

Function

Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.

Summary

AFP Antibody: Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal development. In adults, AFP expression is often associated with hepatoma or teratoma. However, hereditary persistance of AFP may also be found in individuals with no obvious pathology. AFP is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. AFP levels in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of AFP in fetal human liver tissue lysate with AFP antibody at (A) 1 μg/mL and (B) 2 μg/mL.

Immunohistochemistry of AFP in rat liver tissue with AFP antibody at 10 μg/mL.

Immunofluorescence of AFP in rat liver tissue with AFP antibody at 20 μg/mL.

Specification

Quantity

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