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JMJD5 Antibody

Catalog # Availability Size / Price Inquiry
APR06564G 0.1 mg / $695

JMJD5 Antibody

Brand

Leading Biology

Catalog Number

APR06564G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality JMJD5 Antibody.

Molecular Weight

47270 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

JMJD5;

Isotype

IgG

Symbol

JMJD5

GeneID

UniProt ID

Function

Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.

Summary

JMJD5 Antibody: The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. While several JMJD proteins have been identified as being involved in chromatin regulation, histone demethylation and development, the function of JMJD5 has not been identified. JMJD5 is expressed in multiple tissues.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of JMJD5 in human liver tissue lysate with JMJD5 antibody at (A) 1 and (B) 2 μg/mL.

Immunohistochemistry of JMJD5 in rat liver tissue with JMJD5 antibody at 2.5 μg/mL.

Immunofluorescence of JMJD5 in Rat Liver cells with JMJD5 antibody at 20 μg/mL.

Specification

Quantity

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