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MTCH2 Antibody

Catalog # Availability Size / Price Inquiry
APR06528G 0.1 mg / $695

MTCH2 Antibody

Brand

Leading Biology

Catalog Number

APR06528G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MTCH2 Antibody.

Molecular Weight

33499 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion inner membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Target

Mtch2;

Isotype

IgG

GeneID

UniProt ID

Function

The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity).

Summary

MTCH2 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of MTCH2 in 293 cell lysate with MTCH2 antibody at 1 μg/mL.

Immunohistochemistry of MTCH2 in mouse kidney tissue with MTCH2 antibody at 5 μg/mL.

Immunofluorescence of MTCH2 in Mouse Kidney cells with MTCH2 antibody at 20 μg/mL.

Specification

Quantity

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