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IFN-beta Antibody

Catalog # Availability Size / Price Inquiry
APR06450G 0.1 mg / $695

IFN-beta Antibody

Brand

Leading Biology

Catalog Number

APR06450G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IFN-beta Antibody.

Molecular Weight

22294 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse

Target

IFNB1;

Isotype

IgG

Symbol

IFB, IFNB

GeneID

UniProt ID

Function

Has antiviral, antibacterial and anticancer activities.

Summary

IFN-beta Antibody: Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by "Natural IFN-producing cells" (IPCs) as part of the host immune response and can also inhibit the development of tumors. IFN-beta binding by its receptor results in the activation of the tyrosine kinases Jak1 and Tyk2 and phosphorylation of members of the STAT family of transcription factors, leading to the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of IFN-b in A-20 cell lysate with IFN-b antibody at 5 μg/mL.

Immunohistochemistry of IFN-b in human liver tissue with IFN-b antibody at 5 μg/mL.

Immunofluorescence of IFN-beta in Human Liver cells with IFN-beta antibody at 20 μg/mL.

Specification

Quantity

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