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TLR10 Antibody

Catalog # Availability Size / Price Inquiry
APR06341G 0.1 mg / $695

TLR10 Antibody

Brand

Leading Biology

Catalog Number

APR06341G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TLR10 Antibody.

Molecular Weight

94564 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human

Target

TLR10;

Isotype

IgG

GeneID

UniProt ID

Function

Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Summary

TLR10 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR10 is highly homologous to TLRs 1 and 6 and is most highly expressed in lymphoid tissues. Most recently genetic variation in TLR10 has been associated with contributing to asthma risk. It should be noted that TLR10 exists in mice only as a pseudogene.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Images

Western blot analysis of TLR10 in human lymph node cell lysates with TLR10 antibody (IN) at (A) 0.5 and (B) 1 μg/mL.

Immunofluorescence of TLR10 in Daudi cells with TLR10 antibody at 2 μg/mL.

Specification

Quantity

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