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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Glutamate Receptor (Metabotropic) Type 5 (mGluR5) Antibody

Glutamate Receptor (Metabotropic) Type 5 (mGluR5) Antibody

Catalog # Availability Size / Price Inquiry
APC00035G 100 μl / $545

Glutamate Receptor (Metabotropic) Type 5 (mGluR5) Antibody

Brand

Leading Biology

Catalog Number

APC00035G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Glutamate Receptor (Metabotropic) Type 5 (mGluR5) Antibody.

Molecular Weight

132469 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}; Multi-pass membrane protein {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}

Host

Chicken

Species Reactivity

Human, Mouse, Rat

Symbol

GPRC1E, MGLUR5

GeneID

UniProt ID

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, ICC

Images

Glutamate Receptor (Metabotropic) Type 5 (mGluR5) mGluR5-staining of pyramidal and granule cell neurons in the hippocampal formation of an adult transgenic mouse brain (red staining); Green staining is GFP-immunoreactivity under the control of a constitutive actin promoter.</p>

Specification

Quantity

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