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INSIG1 antibody - middle region

Catalog # Availability Size / Price Inquiry
APR00775G 50 μg / $545

INSIG1 antibody - middle region

Brand

Leading Biology

Catalog Number

APR00775G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality INSIG1 antibody - middle region.

Molecular Weight

25kDa

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Sheep, Horse, Bovine, Dog

GeneID

UniProt ID

Function

Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

WB Suggested Anti-INSIG1 Antibody Titration: 0.2-1 μg/ml ELISA Titer: 1:1562500 Positive Control: Human Muscle

Host: Rabbit Target Name: WT1 Sample Tissue: 721_B Antibody Dilution: 1.0μg/mlINSIG2 is supported by BioGPS gene expression data to be expressed in 721_B

Specification

Quantity

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