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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > UHRF2 antibody - N-terminal region

UHRF2 antibody - N-terminal region

Catalog # Availability Size / Price Inquiry
APR00667G 50 μg / $545

UHRF2 antibody - N-terminal region

Brand

Leading Biology

Catalog Number

APR00667G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UHRF2 antibody - N-terminal region.

Molecular Weight

90kDa

Cellular Localization

Antigen Cellular Localization: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00358, ECO:0000269|PubMed:12176013, ECO:0000269|PubMed:23404503}. Note=Enriched at pericentric heterochromatin (PH). This localization is dependent on the interaction with H3K9me3 (By similarity).

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog

Symbol

NIRF, RNF107

GeneID

UniProt ID

Function

E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. E3 SUMO-, but not ubiquitin-, protein ligase for ZNF131.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Images

Human Heart

WB Suggested Anti-UHRF2 Antibody Titration: 0.2-1 μg/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysate

Specification

Quantity

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