> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Hrk AntibodyBrand |
Leading Biology | Catalog Number |
APR00039G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Hrk Antibody.
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Molecular Weight |
9884 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass membrane protein. Mitochondrion
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
Hrk
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Isotype |
Rabbit IgG
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Symbol |
BID3
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GeneID |
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UniProt ID |
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Function |
Promotes apoptosis.
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Summary |
Members of the Bcl-2 family of proteins interact to regulate programmed cell death, or apoptosis. Various homodimers and heterodimers formed by proteins in this family can either promote or inhibit apoptosis. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect on certain hematopoietic cell lines following growth factor withdrawal. Additional apoptotic inhibitors in this family include Bcl-x, Bcl-w, Mcl-1, Bag-1 and A1. Pro-apoptotic members of this family include Bax, Bad, Bak, NBK (Bik), BID and Hrk. Hrk (for harakiri), designated DP5 or neuronal death protein in mouse and rat, contains a BH3 domain with high homology to other Bcl-2 family members but lacks the conserved BH1 and BH2 domains. Physical interaction of Hrk with Bcl-2 or Bcl-xL inhibits the apoptotic activity of Hrk.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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