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B7-H1 / PD-L1 / CD274 Antibody

Catalog # Availability Size / Price Inquiry
APR03374G 50 μl / $495

B7-H1 / PD-L1 / CD274 Antibody

Brand

Leading Biology

Catalog Number

APR03374G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality B7-H1 / PD-L1 / CD274 Antibody.

Molecular Weight

33275 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human

Target

Human B7-H1 / PD-L1 / CD274

Symbol

B7H1, PDCD1L1, PDCD1LG1, PDL1

GeneID

UniProt ID

Function

Involved in the costimulatory signal, essential for T- cell proliferation and production of IL10 and IFNG, in an IL2- dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Summary

Involved in the costimulatory signal, essential for T- cell proliferation and production of IL10 and IFNG, in an IL2- dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (5 - 10 μg/ml), WB (1:500 - 1:2000),

Images

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specification

Quantity

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