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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PLG / Plasmin / Plasminogen Antibody

PLG / Plasmin / Plasminogen Antibody

Catalog # Availability Size / Price Inquiry
APS00016G 100 μg / $495

PLG / Plasmin / Plasminogen Antibody

Brand

Leading Biology

Catalog Number

APS00016G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLG / Plasmin / Plasminogen Antibody.

Molecular Weight

90569 Da

Cellular Localization

Antigen Cellular Localization: Secreted. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin Interaction with HRG tethers it to the cell surface

Host

Sheep

Species Reactivity

Human, Mouse, Rat

Target

Mouse PLG / Plasmin / Plasminogen

GeneID

UniProt ID

Function

Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.

Summary

Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (10 μg/ml), IHC-P (5 μg/ml), WB (10 μg/ml),

Images

Anti-PLG / Plasmin / Plasminogen antibody IHC staining of human liver.

Specification

Quantity

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