> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > VWF / Von Willebrand Factor Antibody (FITC)Brand |
Leading Biology | Catalog Number |
APS00015G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VWF / Von Willebrand Factor Antibody (FITC).
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Molecular Weight |
309265 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules
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Host |
Sheep
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Species Reactivity |
Human
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Target |
Human von Willebrand factor, a glycoprotein synthesized in endothelial cells and megakaryocytes which circulates in the blood associated with factor VIII in a non-covalent complex
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Isotype |
IgG
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Symbol |
F8VWF
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GeneID |
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UniProt ID |
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Function |
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
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Summary |
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P, IHC-Fr
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Dilution |
IHC-Fr (1:50 - 1:100), IHC-P (1:100),
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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