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CD55 Antibody (aa71-330)

Catalog # Availability Size / Price Inquiry
APR03185G 50 μl / $495

CD55 Antibody (aa71-330)

Brand

Leading Biology

Catalog Number

APR03185G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD55 Antibody (aa71-330).

Molecular Weight

41kDa

Cellular Localization

Antigen Cellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted Isoform 5: Secreted Isoform 7: Cell membrane; Lipid-anchor, GPI-anchor

Host

Rabbit

Species Reactivity

Human

Target

Human CD55

Symbol

CR, DAF

GeneID

UniProt ID

Function

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

Summary

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, ICC

Dilution

ICC (1:100-1:1000), IHC-P (5 μg/ml), WB (1:500-1:3000)

Images

Immunofluorescence of methanol-fixed HeLa using CD55 antibody at 1:200 dilution.

Sample (30 ug of whole cell lysate). A: THP-1. 10% SDS PAGE. CD55 antibody diluted at 1:1000.

Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specification

Quantity

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