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HEXIM1 Antibody (aa181-230)

Catalog # Availability Size / Price Inquiry
APR03074G 50 μl / $495

HEXIM1 Antibody (aa181-230)

Brand

Leading Biology

Catalog Number

APR03074G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HEXIM1 Antibody (aa181-230).

Molecular Weight

41kDa

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Binds alpha- importin and is mostly nuclear

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

HEXIM1 Antibody detects endogenous levels of total HEXIM1 protein.

Symbol

CLP1, EDG1, HIS1, MAQ1

GeneID

UniProt ID

Function

Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.

Summary

Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

ELISA (1:10000), IF (1:100-1:500), IHC-P (20 μg/ml), WB (1:500-1:1000) ,

Images

Human, Small intestine: Formalin-Fixed Paraffin-Embedded (FFPE)

Immunofluorescence of HeLa cells, using HEXIM1 Antibody.

Western blot of extracts from NIH-3T3 cells, using HEXIM1 Antibody.

Specification

Quantity

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