> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HEXIM1 Antibody (aa181-230)Brand |
Leading Biology | Catalog Number |
APR03074G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HEXIM1 Antibody (aa181-230).
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Molecular Weight |
41kDa
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Note=Binds alpha- importin and is mostly nuclear
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
HEXIM1 Antibody detects endogenous levels of total HEXIM1 protein.
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Symbol |
CLP1, EDG1, HIS1, MAQ1
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GeneID |
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UniProt ID |
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Function |
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
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Summary |
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Dilution |
ELISA (1:10000), IF (1:100-1:500), IHC-P (20 μg/ml), WB (1:500-1:1000) ,
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Images |
Human, Small intestine: Formalin-Fixed Paraffin-Embedded (FFPE)
Immunofluorescence of HeLa cells, using HEXIM1 Antibody.
Western blot of extracts from NIH-3T3 cells, using HEXIM1 Antibody. |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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