> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TOP2A / Topoisomerase II Alpha Antibody (aa1-50)Brand |
Leading Biology | Catalog Number |
APR02948G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TOP2A / Topoisomerase II Alpha Antibody (aa1-50).
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Molecular Weight |
174kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus, nucleoplasm. Note=Generally located in the nucleoplasm
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
TOP2A Antibody detects endogenous levels of total TOP2A protein.
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Symbol |
TOP2
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GeneID |
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UniProt ID |
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Function |
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).
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Summary |
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Dilution |
ELISA (1:20000), IF (1:100-1:500), IHC-P (10 μg/ml), WB (1:500-1:1000) ,
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Images |
Immunofluorescence of A549 cells, using TOP2A Antibody.
Western blot of extracts from HT-29 cells, using TOP2A Antibody.
Anti-TOP2A antibody IHC of human testis. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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