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SENP1 Antibody (aa1-50)

Catalog # Availability Size / Price Inquiry
APR02941G 50 μl / $495

SENP1 Antibody (aa1-50)

Brand

Leading Biology

Catalog Number

APR02941G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SENP1 Antibody (aa1-50).

Molecular Weight

73kDa

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Shuttles between cytoplasm and nucleus

Host

Rabbit

Species Reactivity

Human, Mouse

Target

SENP1 Antibody detects endogenous levels of total SENP1 protein.

GeneID

UniProt ID

Function

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1.

Summary

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:10000), IHC-P (10 μg/ml), WB (1:500-1:1000)

Images

Western blot of extracts from Jurkat cells, using SENP1 Antibody.

Specification

Quantity

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