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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > KDM8 / JMJD5 / FLJ13798 Antibody (C-Terminus)

KDM8 / JMJD5 / FLJ13798 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR02709G 50 μg / $495

KDM8 / JMJD5 / FLJ13798 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR02709G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KDM8 / JMJD5 / FLJ13798 Antibody (C-Terminus).

Molecular Weight

47kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Human JMJD5

Symbol

JMJD5

GeneID

UniProt ID

Function

Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.

Summary

Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

IHC-P (5 μg/ml), WB (1-2 μg/ml),

Images

Immunofluorescence of JMJD5 in Rat Liver cells with JMJD5 antibody at 20 ug/ml.

Anti-JMJD5 antibody IHC of human breast.

Specification

Quantity

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