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FKTN / Fukutin Antibody

Catalog # Availability Size / Price Inquiry
APR02684G 50 μl / $495

FKTN / Fukutin Antibody

Brand

Leading Biology

Catalog Number

APR02684G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FKTN / Fukutin Antibody.

Molecular Weight

54kDa

Cellular Localization

Antigen Cellular Localization: Golgi apparatus membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human

Target

Human Fukutin. Predicted cross-reactivity based on amino acid sequence homology: mouse (90%), rat (91%).

Symbol

FCMD

GeneID

UniProt ID

Function

Glycosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development.

Summary

Glycosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, ICC

Dilution

ICC (1:100-1:200), IF (1:100-1:200), IHC-P (10 μg/ml), WB (1:500-1:3000) ,

Images

Immunofluorescence of methanol-fixed HeLa, using Fukutin antibody at 1:200 dilution.

Sample (30 ug of whole cell lysate).

Anti-FKTN / Fukutin antibody IHC of human skeletal muscle.

Specification

Quantity

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